SCHEMBL18979086

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17520358	0.97	KDR (0.73)	KDREGFRRETKIF5BHDAC3
	SCHEMBL17520354	0.96	KDR (0.71)	KDREGFRRETKIF5BHDAC3
	SCHEMBL17520330	0.96	KDR (0.74)	KDREGFRRETKIF5BHDAC3
	SCHEMBL19220792	0.91	KDR (0.69)	KDREGFRRETKIF5BHDAC3
	SCHEMBL4109645	0.89	KDR (0.80)	KDREGFRRETKIF5BHDAC3
	SCHEMBL19220786	0.88	HDAC3 (0.69)	KDREGFRHDAC3HDAC4HDAC1
	SCHEMBL17520353	0.88	KDR (0.73)	KDREGFRRETKIF5BHDAC3
	SCHEMBL14964748	0.88	KDR (0.82)	KDREGFRRETKIF5BFGFR1
	SCHEMBL1468281	0.88	KDR (0.82)	KDREGFRRETKIF5BFGFR1
	SCHEMBL19220774	0.87	HDAC3 (0.70)	KDREGFRHDAC3HDAC4HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.