SCHEMBL18979418

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18979466	0.90	RAF1 (0.49)	DYRK1AGSK3BDEGS1ABCB1ABCC1
	SCHEMBL31672288	0.90	RAF1 (0.49)	DYRK1AGSK3BDEGS1ABCB1ABCC1
	SCHEMBL17027868	0.90	DEGS1 (0.47)	DYRK1AGSK3BDEGS1ABCB1ABCC1
	SCHEMBL18979480	0.89	GSK3B (0.46)	DYRK1AGSK3BDEGS1ABCB1ABCC1
	SCHEMBL24187466	0.89	DEGS1 (0.45)	DYRK1AGSK3BDEGS1NPC1RAB9A
	SCHEMBL17027822	0.88	ABCB1 (0.48)	DYRK1AGSK3BDEGS1ABCB1ABCC1
	SCHEMBL18979465	0.88	DEGS1 (0.45)	DYRK1AGSK3BDEGS1ABCB1ABCC1
	SCHEMBL17027778	0.86	DEGS1 (0.47)	DEGS1ABCB1ABCC1
	SCHEMBL18996617	0.86	DEGS1 (0.47)	DYRK1AGSK3BDEGS1ABCB1ABCC1
	SCHEMBL18996618	0.84	KMT2A (0.48)	DYRK1AGSK3BDEGS1ABCB1ABCC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.