⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071382 | 0.82 | — | — | |
| SCHEMBL27097 | 0.82 | — | — | |
| SCHEMBL26413326 | 0.77 | — | — | |
| SCHEMBL28049420 | 0.77 | — | — | |
| SCHEMBL11790145 | 0.76 | — | — | |
| SCHEMBL11867556 | 0.76 | — | — | |
| SCHEMBL9748122 | 0.72 | — | — | |
| SCHEMBL3347195 | 0.72 | — | — | |
| SCHEMBL18773861 | 0.72 | — | — | |
| SCHEMBL5435180 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121465-A | Synthesis process of 2-chloro-5-chloromethyl thiazole | 安徽海顺化工有限公司 | 2021-07-16 | — | — | CN | claimed |
| EP-0244176-A2 | Thienopyrimidine-2,4-dione derivatives and intermediates thereof | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-11-04 | — | — | EP | claimed |
| CN-117500584-A | Reactor and process for preparing isocyanates | 科思创德国股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116693470-A | Histamine H3 receptor inhibitor and medical application thereof | 杭州百诚医药科技股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-113121465-A | Synthesis process of 2-chloro-5-chloromethyl thiazole | 安徽海顺化工有限公司 | 2021-07-16 | — | — | CN | disclosed |
| US-10428083-B2 | Heterocyclylmethyl-thienouracile as antagonists of the adenosine-A2B-receptor | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-10-01 | — | — | US | disclosed |
| US-20180065981-A1 | HETEROCYCLYLMETHYL-THIENOURACILE AS ANTAGONISTS OF THE ADENOSINE-A2B-RECEPTOR | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-03-08 | — | — | US | disclosed |
| US-7939523-B2 | Imidazolidinone and imidazolidinethione derivatives | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2011-05-10 | — | — | US | disclosed |
| US-20090176766-A1 | IMIDAZOLIDINONE AND IMIDAZOLIDINETHIONE DERIVATIVES | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2009-07-09 | — | — | US | disclosed |
| EP-0747357-B1 | Dihydropyridine NPY antagonists: piperidine derivatives | BRISTOL MYERS SQUIBB CO (US) | 2002-01-09 | — | — | EP | disclosed |
| US-5668151-A | USEFUL AS ANOREXIGENIC AGENTS IN PROMOTING WEIGHT LOSS AND TREATING EATING DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-09-16 | — | — | US | disclosed |
| US-5635503-A | TREATMENT OF EATING DISORDERS, PROMOTING WEIGHT LOSS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-06-03 | — | — | US | disclosed |
| EP-0747356-A1 | Dihydropyridine NPY antagonists: piperazine derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0747357-A2 | Dihydropyridine NPY antagonists: piperidine derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0747378-A1 | Dihydropyridine NPY antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5554621-A | Dihydropyridine NPY antagonists: nitrogen heterocyclic derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-09-10 | — | — | US | disclosed |
| US-4707550-A | N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |
| EP-0244176-A2 | Thienopyrimidine-2,4-dione derivatives and intermediates thereof | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-11-04 | — | — | EP | disclosed |
| US-4670560-A | VASODILATING AGENTS, HYPOTENSIVE AGENTS AND/OR CARDIOVASCULAR AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1987-06-02 | — | — | US | disclosed |