Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | HTT | P42858 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | MITF | O75030 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 10/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416417 | 0.91 | MAPT (0.47) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL8309042 | 0.88 | MAPT (0.44) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL8309038 | 0.88 | MAPT (0.44) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL8308542 | 0.86 | MAPT (0.49) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL8308539 | 0.86 | MAPT (0.49) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL8045662 | 0.85 | MAPT (0.50) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL9362287 | 0.80 | MAPT (0.46) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL9362285 | 0.80 | MAPT (0.46) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL11482894 | 0.79 | MAPT (0.48) | MAPTKMT2AHTTSMN1; SMN2MEN1 | |
| SCHEMBL10671410 | 0.77 | MAPT (0.53) | MAPTKMT2AHTTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |