SCHEMBL189853

SCHEMBL189853

FC(F)(F)CCCBr

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2906076 0.97
SCHEMBL593834 0.90
SCHEMBL31077556 0.87
SCHEMBL31077529 0.87
SCHEMBL11248962 0.87
SCHEMBL10769685 0.87
SCHEMBL31077618 0.87
SCHEMBL9364968 0.87
SCHEMBL9260249 0.87
SCHEMBL13265281 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 974 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1200717-A Process for preparing 4-bromo-1,1-difluorbut-1-ene and 2,4-dibromo-1,1,1-trifluorobutane ZENECA LTD (GB) 1998-12-02 CN claimed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
EP-4727546-A2 PROTEOSOME COMPLEX INHIBITORS TARGETING CLPP1P2 PROTEASE The Global Alliance for TB Drug Development, Inc. (US) 2026-04-22 EP disclosed
US-12595408-B2 Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses TOKUYAMA CORPORATION (JP) 2026-04-07 US disclosed
US-20260091029-A1 VMAT2 INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF LUYE INNOMIND PHARMA SHIJIAZHUANG CO LTD (CN) 2026-04-02 US disclosed
US-12565495-B2 VMAT2 inhibitor and preparation method therefor and application thereof LUYE INNOMIND PHARMA SHIJIAZHUANG CO., LTD. (CN) 2026-03-03 US disclosed
US-20260049080-A1 WILD TYPE KIT INHIBITORS BLUEPRINT MEDICINES CORP (US) 2026-02-19 US disclosed
EP-4692071-A1 PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS TOKUYAMA CORPORATION (JP) 2026-02-11 EP disclosed
EP-4642777-A1 INHIBITORS OF KIF18A AND USES THEREOF Insilico Medicine IP Limited (HK) 2025-11-05 EP disclosed
US-12448379-B2 Wild type kit inhibitors BLUEPRINT MEDICINES CORPORATION (US) 2025-10-21 US disclosed
EP-0343777-A1 Thio-substituted aromatic alcohols, preparation, intermediates and use LILLY INDUSTRIES LIMITED (GB) 1989-11-29 EP disclosed
US-4794188-A LIPOXYGENASE INHIBITORS USV PHARMACEUTICAL CORPORATION (US) 1988-12-27 US disclosed
EP-0234500-A1 Antiasthma inhalation compositions RORER PHARMACEUTICAL CORPORATION (US) 1987-09-02 EP disclosed
US-4645838-A Pyrazolopyridine compounds, and intermediates, useful as anxiolytic agents ICI AMERICAS INC. (US) 1987-02-24 US disclosed
EP-0094175-B1 PYRAZOLOPYRIDINE COMPOUNDS ICI AMERICAS INC. (US) 1986-10-29 EP disclosed
US-4563525-A Process for preparing pyrazolopyridine compounds ICI AMERICAS INC. (US) 1986-01-07 US disclosed
US-4552883-A CNS DEPRESSANTS, ANXIOLYTICS ICI AMERICAS INC. (US) 1985-11-12 US disclosed
US-4511568-A CNS-Depressant pyrazolopyridines ICI AMERICAS INC. (US) 1985-04-16 US disclosed
EP-0096995-A2 Pyrazolopyridine compounds ICI AMERICAS INC. (US) 1983-12-28 EP disclosed
EP-0094175-A1 Pyrazolopyridine compounds ICI AMERICAS INC. (US) 1983-11-16 EP disclosed