Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18986527 | 0.80 | BUB1 (0.54) | BUB1 | |
| SCHEMBL18986608 | 0.78 | BUB1 (0.72) | BUB1 | |
| SCHEMBL18986276 | 0.73 | BUB1 (0.70) | BUB1 | |
| SCHEMBL17372067 | 0.72 | BUB1 (1.00) | BUB1 | |
| SCHEMBL18986378 | 0.71 | BUB1 (0.66) | BUB1 | |
| SCHEMBL18986526 | 0.70 | BUB1 (0.54) | BUB1 | |
| SCHEMBL19017431 | 0.67 | BUB1 (0.62) | BUB1 | |
| SCHEMBL19017108 | 0.66 | BUB1 (0.61) | BUB1 | |
| SCHEMBL18986686 | 0.62 | BUB1 (0.71) | BUB1 | |
| SCHEMBL18986441 | 0.62 | BUB1 (0.74) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3390401-A1 | HETERO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | Bayer Pharma Aktiengesellschaft (DE) | 2018-10-24 | — | — | EP | claimed |
| WO-2017102649-A1 | HETERO-1,5,6,7-TETRAHYDRO-4H-INDOL-4-ONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | claimed |