SCHEMBL1899261

SCHEMBL1899261

CC(C)CCNc1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.58
EGFR P00533 3/20 0.58
MAPK1 P28482 3/20 0.58
L3MBTL1 Q9Y468 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
RAB9A P51151 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
PABPC1 P11940 1/20 0.58
MEN1 O00255 4/20 0.57
KMT2A Q03164 4/20 0.57
POLB P06746 4/20 0.57
ALDH1A1 P00352 3/20 0.57
BLM P54132 2/20 0.57
RAD52 P43351 2/20 0.57
LMNA P02545 2/20 0.57
HTT P42858 1/20 0.57
RECQL P46063 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
CYP1A2 P05177 2/20 0.54
CYP2C8 P10632 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1900005 0.89 MEN1 (0.51) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL11134321 0.87 MAPT (0.54) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL30066019 0.84 MAPT (0.60) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL8444246 0.84 MAPT (0.62) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL10781791 0.84 MAPT (0.62) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL11142221 0.83 NSD2 (0.50) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL6291460 0.81 MEN1 (0.64) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL126055 0.81 MAPT (0.59) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL4732627 0.81 MEN1 (0.72) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2
SCHEMBL22410474 0.81 MAPT (0.59) MAPTEGFRMAPK1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2013-01-03 US claimed
EP-2504103-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M Innovative Properties Company (US) 2012-10-03 EP claimed
WO-2011063332-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-26 WO claimed
CN-111514950-A System and method for sample concentration and detection using separation fluid 3M创新有限公司 2020-08-11 CN disclosed
US-10639629-B2 Systems and methods for sample concentration and detection using a separation liquid 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-05-05 US disclosed
US-20200088615-A1 SYSTEMS AND METHODS FOR RAPID DETECTION OF AN ANALYTE OF INTEREST 3M INNOVATIVE PROPERTIES COMPANY 2020-03-19 US disclosed
EP-3551991-A1 SYSTEMS AND METHODS FOR RAPID DETECTION OF AN ANALYTE OF INTEREST 3M Innovative Properties Company (US) 2019-10-16 EP disclosed
EP-2826564-B1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES CO (US) 2018-12-26 EP disclosed
WO-2018106488-A1 SYSTEMS AND METHODS FOR RAPID DETECTION OF AN ANALYTE OF INTEREST 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-06-14 WO disclosed
US-9909969-B2 Systems and methods for detecting an analyte of interest in a sample using microstructured surfaces 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-06 US disclosed
US-9880102-B2 Microwell array articles and methods of use 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-01-30 US disclosed
EP-2726842-B1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES CO (US) 2016-03-16 EP disclosed
US-20160025637-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2016-01-28 US disclosed
EP-2826564-A1 Microwell array articles and methods of use 3M Innovative Properties Company of 3M Center (US) 2015-01-21 EP disclosed
EP-2726842-A1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M Innovative Properties Company (US) 2014-05-07 EP disclosed
US-20140096598-A1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-04-10 US disclosed
WO-2013003308-A1 SYSTEMS AND METHODS FOR DETECTING AN ANALYTE OF INTEREST IN A SAMPLE USING MICROSTRUCTURED SURFACES 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-01-03 WO disclosed
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY 2013-01-03 US disclosed
EP-2504103-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M Innovative Properties Company (US) 2012-10-03 EP disclosed
WO-2011063332-A2 MICROWELL ARRAY ARTICLES AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004967-A1 MICROWELL ARRAY ARTICLES AND METHODS OF USE CD68, ANXA2, ANXA5 MAPT 1788/4885EGFR 3185/4885MAPK1 4675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.