Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18993112 | 0.87 | PPARG (0.41) | MCL1BAK1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1010860 | 0.81 | F2 (0.44) | CYP1A2CYP2C9CYP2C19NPC1CYP3A4 | |
| SCHEMBL14811619 | 0.80 | F10 (0.45) | MAPTL3MBTL1F2NR1H2NR1H3 | |
| SCHEMBL18993132 | 0.79 | CCNT1 (0.38) | MCL1BAK1L3MBTL1EGLN1F2 | |
| SCHEMBL18993114 | 0.77 | MCL1 (0.40) | MCL1BAK1MAPTL3MBTL1EGLN1 | |
| SCHEMBL14810502 | 0.76 | F10 (0.44) | MAPTL3MBTL1NR1H2NR1H3F10 | |
| SCHEMBL1013370 | 0.75 | KDM4E (0.44) | NPC1L3MBTL1TTRMAP4K4NR1H2 | |
| SCHEMBL30657584 | 0.75 | KDM4E (0.44) | NPC1L3MBTL1TTRMAP4K4NR1H2 | |
| SCHEMBL27209650 | 0.75 | F2 (0.39) | CYP1A2CYP2C9CYP2C19MAPTL3MBTL1 | |
| SCHEMBL18422515 | 0.74 | TTR (0.46) | MAPTTTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682953-B2 | Amide compounds, compositions and applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-06-20 | — | — | US | disclosed |