Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.49 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18993235 | 0.84 | CHRM3 (0.50) | CHRM3CARM1PRMT6 | |
| SCHEMBL740042 | 0.82 | CHRM3 (0.75) | CHRM3 | |
| SCHEMBL783740 | 0.78 | CHRM2 (0.46) | CHRM3CARM1PRMT6CHRM2 | |
| SCHEMBL783900 | 0.77 | CHRM3 (0.36) | CHRM3CHRM2 | |
| SCHEMBL783776 | 0.76 | CHRM2 (0.46) | CHRM3CHRM2 | |
| SCHEMBL19215589 | 0.74 | CHRM3 (0.74) | CHRM3 | |
| SCHEMBL783894 | 0.74 | CHRM2 (0.40) | CHRM3CHRM2 | |
| SCHEMBL18239943 | 0.74 | CHRM3 (0.68) | CHRM3 | |
| SCHEMBL693450 | 0.74 | CHRM3 (0.65) | CHRM3 | |
| SCHEMBL693841 | 0.73 | CHRM3 (0.67) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682957-B2 | Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity | THERAVANCE RESPIRATORY COMPANY, LLC (US) | 2017-06-20 | — | — | US | disclosed |