Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 19/20 | 0.91 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16701893 | 0.95 | NR1H4 (1.00) | NR1H4POLBMAPT | |
| SCHEMBL16702100 | 0.92 | NR1H4 (0.88) | NR1H4MAPT | |
| SCHEMBL16702323 | 0.91 | NR1H4 (0.92) | NR1H4POLBMAPT | |
| SCHEMBL16702108 | 0.91 | NR1H4 (0.91) | NR1H4 | |
| SCHEMBL16702370 | 0.91 | NR1H4 (0.91) | NR1H4POLBMAPT | |
| SCHEMBL16702770 | 0.90 | NR1H4 (0.89) | NR1H4POLBMAPT | |
| SCHEMBL18993365 | 0.89 | NR1H4 (0.82) | NR1H4POLBMAPT | |
| SCHEMBL16702189 | 0.87 | NR1H4 (0.81) | NR1H4MAPT | |
| SCHEMBL16702145 | 0.85 | NR1H4 (0.82) | NR1H4POLBMAPT | |
| SCHEMBL16701975 | 0.85 | NR1H4 (1.00) | NR1H4POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682939-B2 | Compositions and methods for modulating farnesoid X receptors | NOVARTIS AG (CH) | 2017-06-20 | — | — | US | disclosed |