Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL408337 | 0.88 | HRH3 (0.34) | MAPK1MEN1KMT2AHRH3 | |
| SCHEMBL408977 | 0.86 | HRH3 (0.32) | MAPK1MEN1KMT2AHRH3 | |
| SCHEMBL21316725 | 0.83 | MAPK1 (0.30) | MAPK1 | |
| SCHEMBL22389189 | 0.80 | MAPK1 (0.32) | MAPK1MEN1KMT2AHRH3 | |
| SCHEMBL26269608 | 0.77 | HRH3 (0.33) | MAPK1MEN1KMT2AHRH3 | |
| SCHEMBL23347753 | 0.77 | HRH3 (0.32) | MEN1KMT2AHRH3 | |
| SCHEMBL21172179 | 0.76 | — | — | |
| SCHEMBL21172177 | 0.76 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL18993481 | 0.75 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL18993493 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682097-B2 | Oligonucleotide analogues targeting human LMNA | SAREPTA THERAPEUTICS, INC. (US) | 2017-06-20 | — | — | US | disclosed |