Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SAE1 | Q9UBE0 | 20/20 | 0.56 |
| ▸ | UBA2 | Q9UBT2 | 20/20 | 0.56 |
| ▸ | NAE1 | Q13564 | 15/20 | 0.56 |
| ▸ | UBA3 | Q8TBC4 | 15/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17410033 | 0.90 | SAE1 (0.70) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL18995203 | 0.89 | SAE1 (0.54) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL18962809 | 0.87 | SAE1 (0.51) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17429148 | 0.84 | SAE1 (0.47) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17410312 | 0.83 | SAE1 (0.74) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17410029 | 0.81 | SAE1 (0.74) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17398680 | 0.81 | SAE1 (0.70) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17421372 | 0.81 | SAE1 (0.70) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL21128801 | 0.81 | SAE1 (0.70) | SAE1UBA2NAE1UBA3 | |
| SCHEMBL17410021 | 0.81 | SAE1 (0.70) | SAE1UBA2NAE1UBA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9683003-B2 | Heteroaryl compounds useful as inhibitors of SUMO activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-06-20 | — | — | US | disclosed |