Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 18/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19184909 | 0.87 | HRH3 (0.39) | HRH3CYP2D6KCNH2 | |
| SCHEMBL26504917 | 0.84 | HRH3 (0.38) | HRH3 | |
| SCHEMBL1106458 | 0.82 | HRH3 (0.40) | HRH3CYP2D6KCNH2 | |
| SCHEMBL19867109 | 0.80 | HRH3 (0.38) | HRH3CYP2D6KCNH2 | |
| SCHEMBL18068058 | 0.78 | HRH3 (0.38) | HRH3CYP2D6KCNH2 | |
| SCHEMBL17973818 | 0.76 | HRH3 (0.39) | HRH3 | |
| SCHEMBL2603278 | 0.74 | HRH3 (0.43) | HRH3 | |
| SCHEMBL15159046 | 0.73 | HRH3 (0.38) | HRH3 | |
| SCHEMBL12026686 | 0.73 | HRH3 (0.39) | HRH3CYP2D6KCNH2 | |
| SCHEMBL10299845 | 0.73 | EPHX1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682141-B2 | Combination of kinase inhibitors and uses thereof | INTELLIKINE LLC (US) | 2017-06-20 | — | — | US | disclosed |