SCHEMBL1899783

SCHEMBL1899783

CCCCC1CC2C=CC1C2.CCCCCCC1CC2C=CC1C2

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.45
ALDH1A1 P00352 4/20 0.45
ALOX5 P09917 1/20 0.40
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HTT P42858 1/20 0.34
TSHR P16473 1/20 0.33
EPHX1 P07099 1/20 0.33
EPHX2 P34913 1/20 0.32
PPARG P37231 1/20 0.30
POLB P06746 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11073764 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL6273014 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL250011 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL11181796 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL144425 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL6268871 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL3165070 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL6258695 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL6260191 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A
SCHEMBL816597 0.98 KDM4E (0.46) KDM4EALDH1A1ALOX5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101563315-B Ring-opening cross-metathesis of cycloolefins with seed oils and the like ELEVANCE RENEWABLE SCIENCES 2013-08-14 CN disclosed
EP-2321363-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS Materia, Inc. (US) 2011-05-18 EP disclosed
WO-2010021740-A1 TELECHELIC OLEFIN METATHESIS POLYMERS FROM RENEWABLE FEEDSTOCKS MATERIA, INC. (US) 2010-02-25 WO disclosed