SCHEMBL1899786

SCHEMBL1899786

CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)[C@H]1C[C@@H](C2CC2)N(C(=O)O)c2ccc(C(F)(F)F)cc21

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6359793 0.90 CETP (0.67) CETP
SCHEMBL5491860 0.90 CETP (0.67) CETP
SCHEMBL6480622 0.89 CETP (0.78) CETP
SCHEMBL993420 0.89 CETP (0.78) CETP
SCHEMBL992510 0.89 CETP (0.79) CETP
SCHEMBL6228889 0.89 CETP (0.79) CETP
SCHEMBL6585674 0.89 CETP (0.64) CETP
SCHEMBL992805 0.89 CETP (0.64) CETP
SCHEMBL6393539 0.87 CETP (0.70) CETP
SCHEMBL993025 0.87 CETP (0.70) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2319509-A1 Method of Inhibiting remnant lipoprotein production Japan Tobacco, Inc. (JP) 2011-05-11 EP disclosed
EP-2316447-A1 Method of inhibiting remnant lipoprotein production Japan Tobacco, Inc. (JP) 2011-05-04 EP disclosed