Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL425225 | 0.75 | MAPT (0.66) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6251169 | 0.71 | MAPT (0.70) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18819415 | 0.70 | MAPT (0.59) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL14955568 | 0.69 | MAPT (0.74) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18537688 | 0.68 | KDM4E (0.60) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL19769220 | 0.66 | MAPT (0.74) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18819408 | 0.66 | MAPT (0.51) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18999975 | 0.65 | KDM4E (0.56) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL18537725 | 0.65 | MAPT (0.76) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL430440 | 0.63 | MAPT (0.74) | MAPTMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181568-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |