Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.79 |
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.76 |
| ▸ | MEN1 | O00255 | 8/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL430245 | 0.93 | MAPT (0.84) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL426200 | 0.93 | MAPT (0.78) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL427912 | 0.92 | MAPT (0.77) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL13392954 | 0.89 | MAPT (0.72) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL13393681 | 0.89 | MAPT (0.72) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL19000235 | 0.87 | MAPT (0.60) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL426621 | 0.86 | MAPT (1.00) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL426544 | 0.86 | MAPT (0.75) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL14955157 | 0.85 | MAPT (0.79) | MAPTALDH1A1KMT2APOLBNPSR1 | |
| SCHEMBL426622 | 0.84 | MAPT (0.77) | MAPTALDH1A1KMT2APOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181568-A1 | THIENOPYRIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF DENGUE VIRUS INFECTIONS | Siga Technologies, Inc. (US) | 2017-06-21 | — | — | EP | disclosed |