SCHEMBL19001472

SCHEMBL19001472

CN(C)CCCNc1ccc2c3c(cccc13)C(=O)NC2=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 2/20 0.51
KDR P35968 2/20 0.51
PDGFRA P16234 1/20 0.51
KMT2A Q03164 8/20 0.50
MEN1 O00255 6/20 0.50
POLB P06746 5/20 0.50
USP2 O75604 3/20 0.50
MAPT P10636 3/20 0.50
NPSR1 Q6W5P4 3/20 0.50
RGS12 O14924 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50
ATM Q13315 1/20 0.50
TLR9 Q9NR96 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
DYRK3 O43781 1/20 0.47
RPS6KB1 P23443 1/20 0.47
EPHA2 P29317 1/20 0.47
FLT4 P35916 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL16213631 0.99 FGFR1 (0.50) FGFR1KDRPDGFRAKMT2AMEN1
SCHEMBL17529464 0.92 FGFR1 (0.53) FGFR1KDRPDGFRAKMT2AMEN1
Hydrochloric Acid SCHEMBL16213593 0.91 FGFR1 (0.52) FGFR1KDRPDGFRAKMT2AMEN1
SCHEMBL16070381 0.86 MEN1 (0.61) FGFR1KDRPDGFRAKMT2AMEN1
Butane SCHEMBL11876142 0.84 MEN1 (0.65) FGFR1KDRPDGFRAKMT2AMEN1
SCHEMBL28495677 0.83 MEN1 (0.60) FGFR1KDRPDGFRAKMT2AMEN1
SCHEMBL5517131 0.83 MEN1 (0.51) FGFR1KDRPDGFRAKMT2AMEN1
SCHEMBL28552747 0.82 MEN1 (0.55) FGFR1KDRPDGFRAKMT2AMEN1
SCHEMBL12463506 0.80 POLB (0.66) FGFR1KDRPDGFRAKMT2AMEN1
SCHEMBL27649471 0.79 MEN1 (0.53) KMT2AMEN1POLBUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017103045-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A STYRYL OR NAPHTHYLAMIDE DIRECT DYE BEARING AN AMINOALKYL FUNCTION, DYEING PROCESS AND DYE L'OREAL (FR) 2017-06-22 WO disclosed
WO-2017103038-A2 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A STYRYL OR NAPHTHYLAMIDE DIRECT DYE BEARING A HYDROXYALKYL FUNCTION, DYEING PROCESS AND DYE L'OREAL (FR) 2017-06-22 WO disclosed