Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19677506 | 0.94 | HIF1A (0.65) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL12267344 | 0.94 | HIF1A (0.65) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL13851882 | 0.91 | HTT (0.65) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL12267213 | 0.90 | HTT (0.57) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL376300 | 0.89 | HIF1A (0.61) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL12267330 | 0.88 | AR (0.74) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL19677385 | 0.88 | AR (0.74) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL13513140 | 0.86 | AR (0.76) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL13513189 | 0.85 | HTT (0.58) | HTTHIF1AARKMT2ALMNA | |
| SCHEMBL13513185 | 0.85 | HTT (0.58) | HTTHIF1AARKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307342-B1 | DIGLYCIDIC ETHER DERIVATIVE THERAPEUTICS AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2017-06-21 | — | — | EP | disclosed |