SCHEMBL19001807

SCHEMBL19001807

c1ccc(-c2ccc(N(c3ccc(-c4cccc5ccccc45)cc3)c3cccc4c3-c3ccccc3C43c4ccccc4-c4c(-c5ccccc5)cccc43)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.36
CA1 P00915 3/20 0.36
CA2 P00918 3/20 0.36
CA9 Q16790 3/20 0.36
PPARG P37231 8/20 0.33
PPARA Q07869 8/20 0.33
TNF P01375 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
PPARD Q03181 1/20 0.33
CYP1A2 P05177 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
MCL1 Q07820 1/20 0.32
ACMSD Q8TDX5 1/20 0.32
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19011248 0.96 CA12 (0.37) CA12CA1CA2CA9PPARG
SCHEMBL19850004 0.96 CA12 (0.37) CA12CA1CA2CA9PPARG
SCHEMBL16810738 0.95 CA12 (0.36) CA12CA1CA2CA9PPARG
SCHEMBL24646418 0.94 CA12 (0.37) CA12CA1CA2CA9PPARG
SCHEMBL21559218 0.93 CA12 (0.35) CA12CA1CA2CA9PPARG
SCHEMBL19001862 0.93 CA12 (0.32) CA12CA1CA2CA9SIGMAR1
SCHEMBL22425422 0.93 CA12 (0.35) CA12CA1CA2CA9PPARG
SCHEMBL25124556 0.93 CA12 (0.37) CA12CA1CA2CA9PPARG
SCHEMBL21559219 0.92 CA12 (0.34) CA12CA1CA2CA9PPARG
SCHEMBL25579023 0.92 CA12 (0.34) CA12CA1CA2CA9PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3390365-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-04-14 EP disclosed
WO-2017102063-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2017-06-22 WO disclosed