Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10330317 | 0.90 | EPHX1 (0.39) | EPHX1KDM4CHDAC3HDAC4HDAC1 | |
| SCHEMBL21780549 | 0.81 | HDAC3 (0.35) | EPHX1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21365174 | 0.79 | EPHX1 (0.42) | EPHX1KDM4CHDAC3HDAC4HDAC1 | |
| SCHEMBL26045019 | 0.76 | EPHX1 (0.36) | EPHX1KDM4CCHEK1DAPK3ROCK2 | |
| SCHEMBL26045016 | 0.74 | KDM4C (0.36) | EPHX1KDM4CCHEK1DAPK3ROCK2 | |
| SCHEMBL25920329 | 0.69 | CHRM2 (0.31) | — | |
| SCHEMBL25920320 | 0.68 | EPHX1 (0.45) | EPHX1KDM4CHDAC3HDAC4HDAC1 | |
| SCHEMBL20026739 | 0.68 | EPHX1 (0.45) | EPHX1KDM4CHDAC3HDAC4HDAC1 | |
| SCHEMBL25920312 | 0.68 | — | — | |
| SCHEMBL25825388 | 0.66 | EPHX1 (0.42) | EPHX1KDM4CHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459171-B1 | Long acting insulin composition | SANOFI AVENTIS DEUTSCHLAND (DE) | 2017-06-21 | — | — | EP | disclosed |