Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002492 | 0.81 | MLLT1 (0.51) | CYP3A4CYP2C19L3MBTL1FAAHKDM4E | |
| SCHEMBL3604597 | 0.80 | KMT2A (0.51) | HPGDALDH1A1KDM4EKMT2AHSD17B10 | |
| SCHEMBL19002501 | 0.80 | HPGD (0.59) | FAAHHPGDALDH1A1HDAC3HDAC8 | |
| SCHEMBL21740798 | 0.80 | HPGD (0.44) | FAAHHPGDALDH1A1TRPV1MEN1 | |
| SCHEMBL12992173 | 0.78 | CYP3A4 (0.68) | CYP3A4CYP2C19L3MBTL1HPGDALDH1A1 | |
| SCHEMBL3600145 | 0.78 | TSHR (0.53) | CYP3A4CYP2C19L3MBTL1FAAHHPGD | |
| SCHEMBL19002537 | 0.77 | CYP3A4 (0.54) | CYP3A4CYP2C19L3MBTL1HPGDALDH1A1 | |
| SCHEMBL18134836 | 0.76 | CYP3A4 (0.65) | CYP3A4CYP2C19L3MBTL1HPGDALDH1A1 | |
| SCHEMBL14753611 | 0.76 | CYP3A4 (0.56) | CYP3A4CYP2C19L3MBTL1FAAHHPGD | |
| SCHEMBL2433131 | 0.75 | MAPT (0.75) | CYP3A4CYP2C19L3MBTL1FAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | MAPK6, MAP3K6, MAPK4 | CYP3A4 4589/4885CYP2C19 4701/4885L3MBTL1 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.