Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 6/20 | 0.44 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1007385 | 0.88 | GRIA2 (0.49) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1900284 | 0.87 | MAPT (0.49) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1006093 | 0.83 | MAPT (0.57) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1891273 | 0.82 | SMN1; SMN2 (0.56) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1006821 | 0.81 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1895488 | 0.78 | MAPT (0.69) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1895722 | 0.78 | MAPT (0.56) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1008025 | 0.78 | MAPT (0.53) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1893494 | 0.77 | POLB (0.54) | MAPTCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL1009106 | 0.77 | GRIA2 (0.54) | MAPTCYP1A2CYP3A4CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | GRIN1, GRM1, GRIK1 | MAPT 4623/4885CYP1A2 2476/4885CYP3A4 2926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.