⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16361929 | 0.71 | — | — | |
| SCHEMBL22041378 | 0.71 | — | — | |
| SCHEMBL12495758 | 0.59 | — | — | |
| SCHEMBL12976351 | 0.59 | GAA (0.40) | — | |
| SCHEMBL13938463 | 0.59 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL7621367 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL18037793 | 0.58 | — | — | |
| SCHEMBL36587 | 0.55 | — | — | |
| SCHEMBL4511207 | 0.55 | — | — | |
| SCHEMBL31476287 | 0.55 | MEN1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11834449-B2 | TYK2 inhibitors and uses thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-12-05 | — | — | US | disclosed |
| WO-2020112937-A1 | TYK2 INHIBITORS AND USES THEREOF | NIMBUS LAKSHMI, INC. (US) | 2020-06-04 | — | — | WO | disclosed |
| WO-2017106647-A1 | PROCESS FOR THE PREPARATION OF TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS FOR USING THE SAME FOR THE TREATMENT OF CANCER | GENENTECH, INC. (US) | 2017-06-22 | — | — | WO | disclosed |