Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 2/20 | 0.66 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.57 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | SSTR2 | P30874 | 7/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 7/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19003328 | 1.00 | PTGER2 (0.66) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL19003327 | 0.97 | PTGER2 (0.71) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL19003323 | 0.97 | PTGER2 (0.71) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL19003325 | 0.97 | PTGER2 (0.71) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL19003414 | 0.97 | PTGER2 (0.71) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL24157885 | 0.97 | PTGER2 (0.71) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL19003390 | 0.96 | PTGER2 (0.64) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL23598422 | 0.95 | PTGER2 (0.66) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL23598514 | 0.95 | PTGER2 (0.63) | PTGER2EGFREPHA2NFKBIAAKT1 | |
| SCHEMBL19003397 | 0.95 | PTGER2 (0.66) | PTGER2EGFREPHA2NFKBIAAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106505-A1 | GAS5 BINDING COMPOUNDS, FORMULATIONS, AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-06-22 | — | — | WO | disclosed |