Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12386910 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL12386911 | 1.00 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL19417440 | 0.98 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL1547848 | 0.98 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3HIF1AHSD17B10 | |
| SCHEMBL11627963 | 0.91 | — | — | |
| SCHEMBL19958821 | 0.91 | — | — | |
| Methane SCHEMBL28084753 | 0.89 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19250499 | 0.84 | — | — | |
| SCHEMBL9353322 | 0.82 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18517104 | 0.79 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9789089-B2 | Therapeutic compounds | GILEAD SCIENCES, INC. (US) | 2017-10-17 | — | — | US | disclosed |
| EP-2348125-B1 | Method for the synthesis of a bifunctional complex | NUEVOLUTION AS (DK) | 2017-06-21 | — | — | EP | disclosed |