Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20585356 | 0.94 | IDO1 (0.67) | IDO1 | |
| SCHEMBL19004394 | 0.94 | IDO1 (0.67) | IDO1 | |
| SCHEMBL20585351 | 0.94 | IDO1 (0.67) | IDO1 | |
| SCHEMBL18991232 | 0.86 | IDO1 (0.68) | IDO1 | |
| SCHEMBL19004276 | 0.86 | IDO1 (0.55) | IDO1 | |
| SCHEMBL18991235 | 0.86 | IDO1 (0.68) | IDO1 | |
| SCHEMBL19004556 | 0.85 | IDO1 (0.54) | IDO1 | |
| SCHEMBL20585221 | 0.84 | IDO1 (0.69) | IDO1 | |
| SCHEMBL20585231 | 0.84 | IDO1 (0.69) | IDO1 | |
| SCHEMBL18991408 | 0.84 | IDO1 (0.69) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017106062-A1 | NOVEL COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2017-06-22 | — | — | WO | disclosed |