Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.39 |
| ▸ | RXRA | P19793 | 8/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | GPR4 | P46093 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27258558 | 0.83 | GRM5 (0.44) | — | |
| SCHEMBL28019841 | 0.79 | KCNH2 (0.39) | ACACBMAPK8GRIN2BRXRAGRIN1 | |
| SCHEMBL1832775 | 0.79 | MCHR1 (0.43) | ACACBMAPK8GRIN2BRXRAGRIN1 | |
| SCHEMBL16815404 | 0.76 | MAPK8 (0.41) | ACACBMAPK8GRIN2BRXRAGRIN1 | |
| SCHEMBL27292062 | 0.76 | GRIN2B (0.36) | GRIN2BRXRAGRIN1ALOX5APFEN1 | |
| SCHEMBL8154440 | 0.75 | MAPK8 (0.41) | MAPK8GRIN2BRXRAGRIN1 | |
| SCHEMBL18112746 | 0.74 | GRIN2B (0.44) | ACACBMAPK8GRIN2B | |
| SCHEMBL13806059 | 0.74 | NPSR1 (0.36) | — | |
| SCHEMBL24142395 | 0.74 | PDE10A (0.51) | ACACBGRIN2B | |
| SCHEMBL16491620 | 0.73 | S1PR4 (0.47) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |