Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.39 |
| ▸ | PI4KA | P42356 | 3/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | PAICS | P22234 | 7/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18986177 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL20732679 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL18986099 | 0.86 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19005196 | 0.84 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19005073 | 0.82 | PIK3CD (0.52) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19005296 | 0.82 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19005273 | 0.82 | PIK3CD (0.50) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19005256 | 0.81 | PIK3CD (0.39) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19005297 | 0.80 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG | |
| SCHEMBL19005148 | 0.80 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPI4KAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102091-A1 | HETEROARYLBENZIMIDAZOLE COMPOUNDS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-06-22 | — | — | WO | disclosed |