SCHEMBL19005528

SCHEMBL19005528

c1nc2nc3n(c2o1)CCNC3

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19005561 0.75 HTR2A (0.31) HTR2AHTR2C
SCHEMBL19005559 0.72 HTR2C (0.34) HTR2AHTR2C
SCHEMBL19005562 0.69 HTR2A (0.31) HTR2AHTR2C
SCHEMBL19005526 0.69 HTR2A (0.34) HTR2AHTR2C
SCHEMBL19005527 0.69 MCHR1 (0.31) HTR2AHTR2C
SCHEMBL31368273 0.68 HTR2C (0.43) HTR2AHTR2C
SCHEMBL19005542 0.66 HTR2A (0.34) HTR2AHTR2C
SCHEMBL19005525 0.66 HTR2C (0.37) HTR2AHTR2C
SCHEMBL19005523 0.64 MCHR1 (0.37) HTR2AHTR2C
SCHEMBL19005520 0.63 HTR2A (0.35) HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017101796-A1 PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2017-06-22 WO disclosed