Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19005523 | 0.76 | MCHR1 (0.37) | MCHR1HTR2AHTR2C | |
| SCHEMBL29539173 | 0.76 | HTR2A (0.50) | MCHR1HTR2AHTR2C | |
| SCHEMBL839815 | 0.76 | HTR2A (0.50) | MCHR1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL20139551 | 0.75 | HTR2A (0.49) | MCHR1HTR2AHTR2C | |
| SCHEMBL19005524 | 0.75 | MCHR1 (0.36) | MCHR1HTR2AHTR2C | |
| SCHEMBL19005552 | 0.71 | MCHR1 (0.36) | MCHR1HTR2AHTR2C | |
| SCHEMBL31164710 | 0.71 | HTR2A (0.56) | MCHR1HTR2AHTR2C | |
| SCHEMBL30138928 | 0.71 | HTT (0.40) | MCHR1HTR2AHTR2C | |
| SCHEMBL31164767 | 0.71 | HTR2A (0.56) | MCHR1HTR2AHTR2C | |
| SCHEMBL12476746 | 0.71 | KDM4E (0.40) | MCHR1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101796-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |