Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377366 | 0.93 | PARP1 (0.73) | PARP1 | |
| SCHEMBL28378754 | 0.92 | PARP1 (0.69) | PARP1 | |
| SCHEMBL10025672 | 0.86 | PARP1 (0.73) | PARP1 | |
| SCHEMBL29416785 | 0.86 | PARP1 (0.73) | PARP1 | |
| SCHEMBL19005802 | 0.84 | PARP1 (0.75) | PARP1 | |
| SCHEMBL19005810 | 0.83 | PARP1 (0.68) | PARP1 | |
| SCHEMBL10025550 | 0.82 | PARP1 (1.00) | PARP1 | |
| SCHEMBL30888480 | 0.82 | PARP1 (1.00) | PARP1 | |
| SCHEMBL10025616 | 0.82 | PARP1 (0.76) | PARP1 | |
| SCHEMBL19569971 | 0.82 | PARP1 (0.90) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207504-B | Phthalazinone derivatives, preparation method and use thereof | 四川科伦博泰生物医药股份有限公司 | 2020-03-10 | — | — | CN | disclosed |
| WO-2017101796-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |