Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28377418 | 0.90 | PARP1 (0.75) | PARP1 | |
| SCHEMBL19005603 | 0.89 | PARP1 (0.70) | PARP1 | |
| SCHEMBL19005837 | 0.89 | PARP1 (0.68) | PARP1 | |
| SCHEMBL19005236 | 0.86 | PARP1 (0.71) | PARP1 | |
| SCHEMBL19005694 | 0.85 | PARP1 (0.72) | PARP1 | |
| SCHEMBL10025570 | 0.84 | PARP1 (0.67) | PARP1 | |
| SCHEMBL19005723 | 0.84 | PARP1 (0.72) | PARP1 | |
| SCHEMBL28378755 | 0.81 | PARP1 (0.74) | PARP1 | |
| SCHEMBL30980032 | 0.81 | TNKS (0.72) | PARP1 | |
| SCHEMBL30888475 | 0.81 | PARP1 (1.00) | PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101796-A1 | PHTHALAZINONE DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2017-06-22 | — | — | WO | disclosed |