Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 9/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.80 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006316 | 0.94 | PIK3CD (0.89) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006191 | 0.93 | PIK3CD (0.87) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006285 | 0.90 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006195 | 0.90 | PIK3CD (0.83) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006288 | 0.89 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006304 | 0.88 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006292 | 0.88 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006244 | 0.87 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006194 | 0.87 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006294 | 0.87 | PIK3CD (0.92) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |