Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.60 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.57 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.52 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18988704 | 0.92 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL19006199 | 0.91 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL19006180 | 0.90 | PIK3CD (0.61) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL19006279 | 0.90 | PIK3CD (0.55) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL19006299 | 0.89 | PIK3CD (0.70) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006242 | 0.88 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006197 | 0.87 | PIK3CD (0.61) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL18988637 | 0.84 | PIK3CD (0.58) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL18988492 | 0.84 | PIK3CD (0.59) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 | |
| SCHEMBL18988662 | 0.84 | PIK3CD (0.57) | PIK3CDPIK3CAPIK3CBPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |