Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.75 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.73 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.71 |
| ▸ | PIK3CB | P42338 | 5/20 | 0.71 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18988930 | 0.96 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL18988932 | 0.96 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19006240 | 0.95 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19006311 | 0.94 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19006307 | 0.94 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19006170 | 0.94 | PIK3CD (0.82) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19006241 | 0.92 | PIK3CD (0.79) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19006290 | 0.92 | PIK3CD (0.76) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL19006281 | 0.91 | PIK3CD (0.75) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 | |
| SCHEMBL18988868 | 0.91 | PIK3CD (0.74) | PIK3CDPIK3CAPIK3CGPIK3CBPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |