Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.68 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.68 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19006194 | 0.94 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006316 | 0.87 | PIK3CD (0.89) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988603 | 0.87 | PIK3CD (0.71) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006244 | 0.87 | PIK3CD (0.77) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006243 | 0.85 | PIK3CD (0.78) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18988551 | 0.82 | PIK3CD (0.48) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL19006245 | 0.82 | PIK3CD (0.75) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17397216 | 0.82 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17401134 | 0.82 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17401190 | 0.82 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017103825-A1 | QUINOLIZINONE DERIVATIVES AS PI3K INHIBITORS | LUPIN LIMITED (IN) | 2017-06-22 | — | — | WO | disclosed |