⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL129840 | 0.83 | — | — | |
| SCHEMBL128005 | 0.81 | TSHR (0.39) | — | |
| SCHEMBL4492021 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL4492282 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL4486439 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL4505354 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL4482866 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL3836866 | 0.79 | TSHR (0.42) | — | |
| SCHEMBL7311713 | 0.78 | — | — | |
| SCHEMBL1416121 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548900-B2 | Oxazino-quinazoline and oxazino-quinoline type compound, preparation method and uses thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-01-10 | — | — | US | claimed |
| CN-112442045-B | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2022-02-18 | — | — | CN | claimed |
| EP-3760633-B1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2021-12-15 | — | — | EP | claimed |
| CN-110229171-B | Oxazinoquinazoline and oxazinoquinoline compound and preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2021-03-12 | — | — | CN | claimed |
| CN-112442045-A | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2021-03-05 | — | — | CN | claimed |
| US-20210040114-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINOLINE TYPE COMPOUND, PREPARATION METHOD AND USES THEREOF | ACCSALUS BIOSCIENCES LIMITED (VG) | 2021-02-11 | — | — | US | claimed |
| EP-3760633-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2021-01-06 | — | — | EP | claimed |
| CN-110229172-B | Acyl-substituted oxazine quinazoline compound, preparation method and application thereof | 北京赛特明强医药科技有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-111718332-A | 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof | 北京赛特明强医药科技有限公司 | 2020-09-29 | — | — | CN | claimed |
| WO-2020187292-A1 | 2-SUBSTITUTED PYRAZOLEAMINO-4-SUBSTITUTED AMINO-5-PYRIMIDINE FORMAMIDE COMPOUND, COMPOSITION AND USE THEREOF | 北京赛特明强医药科技有限公司 | 2020-09-24 | — | — | WO | claimed |
| WO-2019170088-A1 | OXAZINO-QUINAZOLINE AND OXAZINO-QUINAZOLINE TYPE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-09-12 | — | — | WO | claimed |
| WO-2019170086-A1 | ACYL-SUBSTITUTED OXAZINO-QUINAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-09-12 | — | — | WO | claimed |
| EP-1975164-B1 | Octahydrobenzimidazolone compounds as analgetics | EURO CELTIQUE SA (LU) | 2010-01-27 | — | — | EP | claimed |
| EP-1379246-B1 | NOCICEPTIN ANALOGS | EURO CELTIQUE SA (LU) | 2008-10-08 | — | — | EP | claimed |
| US-4648898-A | DIAMINO-DIFLUOROMETHYLTHIOTRIAZINES | SHIONOGI & CO., LTD. (JP) | 1987-03-10 | — | — | US | claimed |
| EP-3901147-B1 | ACYLAMINO BRIDGED HETEROCYCLIC COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2023-11-22 | — | — | EP | disclosed |
| EP-3322417-B1 | TARGETING EMOPAMIL BINDING PROTEIN (EBP) WITH SMALL MOLECULES THAT INDUCE AN ABNORMAL FEEDBACK RESPONSE BY LOWERING ENDOGENOUS CHOLESTEROL BIOSYNTHESIS | UNIV TEXAS (US) | 2023-08-23 | — | — | EP | disclosed |
| US-4504484-A | Certain N,N-di-substituted-pyridine carboxamides, fungicidal compositions and fungicidal method of use | CHEVRON RESEARCH COMPANY (US) | 1985-03-12 | — | — | US | disclosed |
| US-4260624-A | Fungicidal 2-substituted-3-oxa-3a lambda4,4-dithia-6-chloro-1,5-diazapentalene | CHEVRON RESEARCH COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4209610-A | POLYETHYLENE TEREPHTHALATE, ANTISOILANTS, WATER AND OIL REPELLENCY | MARES FRANK (US) | 1980-06-24 | — | — | US | disclosed |