SCHEMBL19008525

SCHEMBL19008525

c1ccc2cc(-c3c4ccccc4c(-c4ccc5ccccc5c4)c4cc(-c5cnc6ccccc6c5)ccc34)ccc2c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 5/20 0.52
PIK3CD O00329 4/20 0.52
MTOR P42345 4/20 0.52
PIK3CB P42338 2/20 0.52
PIK3CG P48736 2/20 0.52
PDGFRB P09619 3/20 0.50
PDGFRA P16234 3/20 0.50
BIRC5 O15392 1/20 0.50
PRMT5 O14744 1/20 0.48
WDR77 Q9BQA1 1/20 0.48
CYP2A6 P11509 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
MAP4K4 O95819 1/20 0.45
CSNK1G2 P78368 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45
MKNK2 Q9HBH9 1/20 0.45
MAP4K5 Q9Y4K4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246769 0.99 PDGFRB (0.53) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL12571764 0.95 PDGFRB (0.47) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL13759442 0.95 PIK3CA (0.51) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL13759451 0.93 PDGFRB (0.51) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL24403781 0.91 PDGFRB (0.57) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL19562262 0.91 PDGFRB (0.51) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL13759464 0.91 CYP2A6 (0.46) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL2601568 0.91 PIK3CA (0.44) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL13759448 0.90 PDGFRB (0.43) PIK3CAPIK3CDMTORPIK3CBPIK3CG
SCHEMBL13979068 0.89 PDGFRB (0.53) PIK3CAPIK3CDMTORPIK3CBPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170179395-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed
US-20170179395-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-06-22 US disclosed