Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.55 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | CCKAR | P32238 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832936 | 0.93 | PTGDR2 (0.62) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL832935 | 0.93 | PTGDR2 (0.62) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL832527 | 0.91 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL832526 | 0.91 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL830820 | 0.91 | PTGDR2 (0.70) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL830821 | 0.91 | PTGDR2 (0.70) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL834132 | 0.89 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL833109 | 0.89 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL833110 | 0.89 | PTGDR2 (0.66) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL834123 | 0.88 | PTGDR2 (0.67) | PTGDR2TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316824-A1 | (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates | Actelion Pharmaceuticals Ltd. (CH) | 2011-05-04 | — | — | EP | disclosed |