Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16882962 | 0.81 | GRM5 (0.43) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL24556771 | 0.79 | TRPV1 (0.34) | GRM5SQORTRPV1PDK2 | |
| SCHEMBL14425847 | 0.78 | KDM4E (0.50) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL14425850 | 0.78 | KDM4E (0.50) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL14425857 | 0.78 | KDM4E (0.50) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL14425848 | 0.78 | KDM4E (0.50) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL11927621 | 0.78 | TRPV1 (0.52) | GRM5KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL22448079 | 0.77 | GRM5 (0.39) | GRM5KDM4ELMNATP53SMN1; SMN2 | |
| SCHEMBL21338505 | 0.76 | TRPV1 (0.45) | KDM4ETP53SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21334236 | 0.76 | KDM4E (0.52) | GRM5KDM4ELMNATP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102052-A1 | FORMULATIONS CONTAINING A SOLID SOLVENT | MERCK PATENT GMBH (DE) | 2017-06-22 | — | — | WO | disclosed |