SCHEMBL1901173

SCHEMBL1901173

CCc1nc(C)n(CC)c1C

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
MAPK1 P28482 2/20 0.38
HSD17B10 Q99714 2/20 0.38
ALOX15 P16050 1/20 0.38
CASP1 P29466 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
RAD52 P43351 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
HTT P42858 1/20 0.32
TP53 P04637 1/20 0.32
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9692394 0.75 KDM4E (0.46) KDM4EMAPK1HSD17B10ALOX15CASP1
SCHEMBL31316476 0.73 KDM4E (0.44) KDM4EMAPK1HSD17B10ALOX15CASP1
SCHEMBL12344036 0.73 GAA (0.34)
SCHEMBL12251590 0.68
Zinc Ion SCHEMBL31316472 0.67 KDM4E (0.39) KDM4EMAPK1HSD17B10ALOX15CASP1
Zinc Ion SCHEMBL31316471 0.67 KDM4E (0.39) KDM4EMAPK1HSD17B10ALOX15CASP1
SCHEMBL23213871 0.67 KDM4E (0.34) KDM4EMAPK1HSD17B10ALOX15CASP1
SCHEMBL13384277 0.63 CYP1A2 (0.39) KDM4EMAPK1HSD17B10ALOX15CASP1
SCHEMBL16239634 0.62 TDP1 (0.41) KDM4EMAPK1HSD17B10ALOX15CASP1
SCHEMBL10111171 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3232455-B1 NONAQUEOUS ELECTROLYTE SOLUTION FOR ELECTRIC DOUBLE LAYER CAPACITORS OTSUKA CHEMICAL CO LTD (JP) 2023-10-25 EP disclosed
US-10593488-B2 Nonaqueous electrolytic solution for electric double layer capacitors OTSUKA CHEMICAL CO., LTD. (JP) 2020-03-17 US disclosed
US-20170330700-A1 NONAQUEOUS ELECTROLYTIC SOLUTION FOR ELECTRIC DOUBLE LAYER CAPACITORS OTSUKA CHEMICAL CO., LTD. (JP) 2017-11-16 US disclosed
EP-3232455-A1 NONAQUEOUS ELECTROLYTE SOLUTION FOR ELECTRIC DOUBLE LAYER CAPACITORS Otsuka Chemical Co., Ltd. (JP) 2017-10-18 EP disclosed
EP-1548769-B1 ELECTROLYTE FOR ELECTROCHEMICAL CAPACITOR AND ELECTROCHEMICAL CAPACITOR CONTAINING THE SAME SANYO CHEMICAL IND LTD (JP) 2011-05-25 EP disclosed
US-20100321863-A1 ACTIVATED CARBON AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-23 US disclosed
US-7785495-B2 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-31 US disclosed
EP-2093191-A1 ACTIVATED CARBON AND METHOD FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-08-26 EP disclosed
US-20090103241-A1 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-04-23 US disclosed
EP-1905740-A1 ELECTRIC DOUBLE LAYER CAPACITOR Sumitomo Chemical Company, Limited (JP) 2008-04-02 EP disclosed
US-7099146-B2 Electrolyte for electrochemical capacitor and electrochemical capacitor containing the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-29 US disclosed
US-20060087798-A1 Electrolyte for electrochemical capacitor and electrochemical capacitor containing the same SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-04-27 US disclosed
EP-1548769-A1 ELECTROLYTE FOR ELECTROCHEMICAL CAPACITOR AND ELECTROCHEMICAL CAPACITOR CONTAINING THE SAME SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090103241-A1 Activated carbon prepared by carbonizing and activating a calixarene containing dihydroxybenzene rings; especially calcining at 400 degrees C. or less in the presence of an oxidative gas, calcining at 1500 degrees or less in an inactive gas, and then further calcining at 200-1500 degrees in H2O or CO2 CBR1, CYP24A1, CALU KDM4E 2457/4885MAPK1 1117/4885HSD17B10 308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.