Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.31 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22092724 | 0.84 | FFAR1 (0.46) | FFAR1PDK2DGAT1UCHL1 | |
| SCHEMBL17785673 | 0.81 | FFAR1 (0.54) | FFAR1PDK2DGAT1UCHL1 | |
| SCHEMBL29663427 | 0.78 | FFAR1 (0.57) | FFAR1PDK2USP30DGAT1 | |
| SCHEMBL1853942 | 0.77 | FFAR1 (0.57) | FFAR1PDK2 | |
| SCHEMBL1872577 | 0.77 | FFAR1 (0.57) | FFAR1PDK2 | |
| SCHEMBL381301 | 0.77 | FFAR1 (0.46) | FFAR1USP30DGAT1AAK1UCHL1 | |
| SCHEMBL29663140 | 0.76 | FFAR1 (0.49) | FFAR1PDK2USP30DGAT1 | |
| SCHEMBL29663127 | 0.76 | FFAR1 (0.49) | FFAR1PDK2USP30DGAT1 | |
| SCHEMBL25826382 | 0.76 | FFAR1 (0.46) | FFAR1PDK2USP30DGAT1AAK1 | |
| SCHEMBL520617 | 0.74 | FFAR1 (0.57) | FFAR1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496558-A1 | THETRAHYDROQUINOLINES DERIVATIVES AS BROMODOMAIN INHIBITORS | GlaxoSmithKline LLC (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011054848-A1 | THETRAHYDROQUINOLINES DERIVATIVES AS BROMODOMAIN INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-05-12 | — | — | WO | disclosed |