Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 19/20 | 0.57 |
| ▸ | BCL2 | P10415 | 14/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20305899 | 0.83 | BCL2L1 (0.66) | BCL2L1BCL2 | |
| SCHEMBL20306172 | 0.82 | BCL2L1 (0.78) | BCL2L1BCL2BAD | |
| SCHEMBL22409476 | 0.78 | BCL2L1 (0.71) | BCL2L1BCL2BAD | |
| SCHEMBL22409479 | 0.78 | BCL2L1 (0.71) | BCL2L1BCL2BAD | |
| SCHEMBL30688250 | 0.77 | BCL2L1 (0.54) | BCL2L1BCL2BAD | |
| SCHEMBL17955529 | 0.77 | BCL2L1 (0.58) | BCL2L1BCL2BAD | |
| SCHEMBL19261433 | 0.75 | BCL2L1 (0.72) | BCL2L1BCL2BAD | |
| SCHEMBL19014952 | 0.75 | NPC1 (0.43) | — | |
| SCHEMBL19263461 | 0.74 | BCL2L1 (0.84) | BCL2L1BCL2BAD | |
| SCHEMBL19145119 | 0.74 | BCL2L1 (0.84) | BCL2L1BCL2BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101851-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | UNITY BIOTECHNOLOGY, INC. (US) | 2017-06-22 | — | — | WO | disclosed |