⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26841313 | 0.96 | — | — | |
| SCHEMBL21450643 | 0.88 | MC4R (0.34) | — | |
| SCHEMBL18870129 | 0.85 | MC4R (0.33) | — | |
| SCHEMBL12317537 | 0.81 | MC4R (0.31) | — | |
| SCHEMBL26058035 | 0.75 | MC4R (0.31) | — | |
| SCHEMBL16596840 | 0.74 | CYP3A4 (0.34) | — | |
| SCHEMBL14156852 | 0.74 | CYP3A4 (0.34) | — | |
| SCHEMBL14157766 | 0.73 | IDO1 (0.35) | — | |
| SCHEMBL23888763 | 0.72 | MC4R (0.31) | — | |
| SCHEMBL15363058 | 0.72 | CYP3A4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017101851-A1 | ACYLSULFONAMIDE DERIVATIVES FOR TREATING SENESCENCE-ASSOCIATED DISEASES AND DISORDERS | UNITY BIOTECHNOLOGY, INC. (US) | 2017-06-22 | — | — | WO | disclosed |