Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | BMX | P51813 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29357876 | 0.81 | PTGS1 (0.42) | TDP1PLK1CTSKLTA4HDPP7 | |
| SCHEMBL7888842 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2TDP1TSHRCTSKBMX | |
| SCHEMBL27503400 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2TDP1TSHR | |
| SCHEMBL27561734 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2TDP1TSHR | |
| SCHEMBL28743140 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2TDP1TSHR | |
| SCHEMBL6897869 | 0.78 | TSHR (0.41) | SMN1; SMN2TDP1TSHRLTA4HDPP7 | |
| SCHEMBL15462640 | 0.78 | SMN1; SMN2 (0.37) | SMN1; SMN2TDP1TSHRCTSK | |
| SCHEMBL20998091 | 0.78 | DPP7 (0.39) | PLK1CTSKDPP7 | |
| SCHEMBL27598566 | 0.77 | TDP1 (0.45) | SMN1; SMN2TDP1TSHRMAPTCACNA1B | |
| SCHEMBL3151254 | 0.77 | TDP1 (0.45) | SMN1; SMN2TDP1TSHRMAPTCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2288615-B1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-06-21 | — | — | EP | disclosed |