Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.71 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901648 | 1.00 | PTGDR2 (0.71) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL1904443 | 0.93 | PTGDR2 (0.62) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL1904444 | 0.93 | PTGDR2 (0.62) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL1903879 | 0.90 | PTGDR2 (0.56) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL1902243 | 0.87 | PTGDR2 (0.54) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL1902244 | 0.87 | PTGDR2 (0.54) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL1901892 | 0.86 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP2C9 | |
| SCHEMBL1900286 | 0.86 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL1903891 | 0.86 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL1901890 | 0.86 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |
| EP-2316824-A1 | (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates | Actelion Pharmaceuticals Ltd. (CH) | 2011-05-04 | — | — | EP | disclosed |