SCHEMBL1901919

SCHEMBL1901919

C=CC(=O)NC(C(C)CC(C)(C)C)S(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2031086 0.82 TSHR (0.47) TSHRZDHHC20ZDHHC2
SCHEMBL9606649 0.81 TSHR (0.46) TSHRZDHHC20ZDHHC2
SCHEMBL3077692 0.79 TSHR (0.44) TSHRZDHHC20ZDHHC2
SCHEMBL162366 0.78 TSHR (0.54) TSHRZDHHC20ZDHHC2
Tert-Butylamine SCHEMBL11693814 0.78 TSHR (0.46) TSHR
SCHEMBL3952450 0.76 TSHR (0.52) TSHRZDHHC20ZDHHC2
Ammonia Solution, Strong SCHEMBL7618985 0.76 TSHR (0.52) TSHRZDHHC20ZDHHC2
Lithium SCHEMBL38660899 0.76 TSHR (0.52) TSHRZDHHC20ZDHHC2
SCHEMBL1775598 0.76 TSHR (0.52) TSHRZDHHC20ZDHHC2
SCHEMBL285065 0.76 TSHR (0.52) TSHRZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108947375-A Hardening accelerator composition comprising a plasticizer 建筑研究和技术有限公司 2018-12-07 CN claimed
EP-3474815-A1 PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2019-05-01 EP disclosed
CN-104995222-B Water soluble hydrophobically associating copolymers with hydrophobically associating monomers 巴斯夫欧洲公司 2018-10-02 CN disclosed
WO-2017220676-A1 PROCESS FOR TREATING KERATIN FIBERS USING AN ANHYDROUS COMPOSITION COMPRISING A COMPOUND OF AZOMETHINE TYPE COMPRISING TWO PYRAZOLOPYRIDINE UNITS AND AN AQUEOUS COMPOSITION L'OREAL (FR) 2017-12-28 WO disclosed
WO-2017186685-A1 METHOD FOR PREPARING AN AQUEOUS POLYACRYLAMIDE SOLUTION BASF SE (DE) 2017-11-02 WO disclosed
WO-2016001239-A1 COMPOSITION COMPRISING AN AQUEOUS PHASE AND A FATTY PHASE THAT ARE VISUALLY DISTINCT L'OREAL (FR) 2016-01-07 WO disclosed
EP-2579946-A2 COLORED AQUEOUS COSMETIC COMPOSITIONS L'Oréal (FR) 2013-04-17 EP disclosed
EP-2496535-A2 WATER-SOLUBLE, HYDROPHOBICALLY ASSOCIATING NANOCOMPOSITES (AS RHEOLOGY MODIFIERS FOR APPLICATIONS IN CONSTRUCTION CHEMISTRY) Construction Research & Technology GmbH (DE) 2012-09-12 EP disclosed
WO-2011054730-A2 WATER-SOLUBLE, HYDROPHOBICALLY ASSOCIATING NANOCOMPOSITES (AS RHEOLOGY MODIFIERS FOR APPLICATIONS IN CONSTRUCTION CHEMISTRY) CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2011-05-12 WO disclosed