Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL833097 | 0.83 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL833098 | 0.83 | PTGDR2 (0.64) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL834000 | 0.77 | BRD3 (0.50) | PTGDR2TBXA2R | |
| SCHEMBL2489729 | 0.70 | PTGDR2 (0.47) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL1907504 | 0.70 | PTGDR2 (0.47) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL831286 | 0.67 | KDM4E (0.48) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL2494169 | 0.67 | PTGDR2 (0.42) | PTGDR2TBXA2R | |
| SCHEMBL5445899 | 0.67 | MAPT (0.51) | PTGDR2AKR1B1PTGDR | |
| SCHEMBL833391 | 0.66 | PTGDR2 (0.67) | PTGDR2TBXA2RPTGDR | |
| SCHEMBL833392 | 0.66 | PTGDR2 (0.67) | PTGDR2TBXA2RPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2316824-A1 | (3-Amino-1,2,3,4-tetrahydro-9H-carbazoI-9-yl)-acetic acid derivates | Actelion Pharmaceuticals Ltd. (CH) | 2011-05-04 | — | — | EP | disclosed |