SCHEMBL19020197

SCHEMBL19020197

CC(C)(C)c1ccc(OP(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c(C(C)(C)C)c1.Cl[Au]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
CYP2C19 P33261 1/20 0.36
KDM4E B2RXH2 4/20 0.35
TSHR P16473 1/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 2/20 0.33
KCNH2 Q12809 1/20 0.33
MAPK1 P28482 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30267754 1.00 APEX1 (0.39) APEX1CA1CA2CA9CYP2C19
SCHEMBL29349873 0.94 CA1 (0.41) APEX1CA1CA2CA9CYP2C19
SCHEMBL26607 0.94 CA1 (0.41) APEX1CA1CA2CA9CYP2C19
Potassium SCHEMBL31621706 0.93 CA1 (0.40) APEX1CA1CA2CA9CYP2C19
Phosphine SCHEMBL7943984 0.93 CA1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL30366575 0.93 CA1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL5608973 0.93 CA1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL31720630 0.93 CA1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL19514039 0.93 CA1 (0.40) APEX1CA1CA2CA9CYP2C19
SCHEMBL29616890 0.93 CA1 (0.40) APEX1CA1CA2CA9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230374178-A1 POST-POLYMERIZATION AND POLYMERIC MATERIAL MODIFICATION THROUGH GOLD CATALYSIS AND POLYMERIC MATERIALS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2023-11-23 US disclosed
WO-2022087516-A1 POST-POLYMERIZATION AND POLYMERIC MATERIAL MODIFICATION THROUGH GOLD CATALYSIS AND POLYMERIC MATERIALS THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2022-04-28 WO disclosed
EP-3184674-A1 DNA-ENCODED CHEMICAL LIBRARY, USE THEREOF AND METHOD TO SYNTHESIZE THE LIBRARY Technische Universität Dortmund (DE) 2017-06-28 EP disclosed